Biopreme has developed a patented injection adapter that introduces negative-pressure tissue stabilization and fixed-depth mechanical guidance into subcutaneous injection delivery.
The device modifies the physical interface between syringe, needle, and tissue to create a controlled and repeatable injection environment independent of user technique.
Design Objectives
Our technology is engineered to address fundamental mechanical limitations of conventional subcutaneous injection, namely:
System Architecture
Biopreme’s adapter consists of three integrated functional subsystems. These subsystems operate sequentially and synergistically during injection.
Negative-pressure stabilization chamber
Fixed-depth penetration channel
Needle concealment housing
Mechanism of Operation
This sequence produces a mechanically guided injection event with reduced dependence on user technique
Attach to Syringe
The adapter is attached to a standard syringe and needle assembly.
Skin Contact
Upon contact with skin, gentle negative pressure is generated within the stabilization chamber.
Negative Pressure Engages
Tissue is drawn into a defined geometry, limiting lateral and vertical movement.
Fixed-Depth Guidance
A fixed-depth channel guides needle advancement to a predetermined subcutaneous depth (3mm).
Injection Delivery
The needle remains concealed within the housing until tissue engagement occurs.
Negative-Pressure Stabilization
Negative pressure serves two primary mechanical functions:
Stabilization improves consistency of needle entry angle and depth while reducing the likelihood of partial insertion or deflection.
Fixed-Depth Mechanical Guidance
The adapter incorporates a depth-regulating channel that physically limits needle penetration to a predetermined subcutaneous depth. Benefits include:
Needle Concealment
The needle is enclosed within the adapter housing prior to engagement with tissue. This configuration:
Eliminates pre-insertion needle visibility
Reduces visual stimulus associated with anxiety | Supports calmer patient experience
Performance Characteristics
Intended Use Environments
Platform Applications
The negative-pressure stabilization architecture is applicable to any subcutaneous injection scenario requiring:Controlled penetration depth · Tissue stabilization · Reduced visual needle exposureThis architecture supports adaptation across multiple therapeutic areas and care settings.